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<t>Oxybenzone</t> excretion stratified by CLDN1 rs893051 variant genotype. An excretion curve is plotted for each individual based on the excretion rate at the measured timepoints. (A–C) Excretion curves of individuals with differing genotypes at CLDN1 rs893051. (A) Individuals homozygous for the minor genotype. (B) Individuals with the heterozygous genotype. (C) Individuals homozygous for the major genotype.
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MS fragmentation analysis of the deuterium labeled A1:F3 metabolite, produced in phytol-d6 feeding experiment. (A) Top: Detected ions of A1:F3 corresponding to (1) [M+Na] + , (2) [M-H2O+H]+ and (3) [M-2H2O+H]+. Middle: Fragmentation spectrum (MS 2 ) of (3). (B) Inferred structures of detected ions in the panel A, with broken C-C bonds indicated by the dashed line.

Journal: bioRxiv

Article Title: Resolving Phytophthora α2 hormone biosynthesis reveals species-specific mechanisms for mating type regulation

doi: 10.64898/2026.04.23.720443

Figure Lengend Snippet: MS fragmentation analysis of the deuterium labeled A1:F3 metabolite, produced in phytol-d6 feeding experiment. (A) Top: Detected ions of A1:F3 corresponding to (1) [M+Na] + , (2) [M-H2O+H]+ and (3) [M-2H2O+H]+. Middle: Fragmentation spectrum (MS 2 ) of (3). (B) Inferred structures of detected ions in the panel A, with broken C-C bonds indicated by the dashed line.

Article Snippet: To facilitate identification of phytol-derived metabolites, a 100 ml culture of the two strains was prepared containing either unlabeled or deuterium-labeled phytol (Toronto Research Chemicals Inc, Cat. No. TRC-T398919) at 3.4 mM.

Techniques: Labeling, Produced

Journal: bioRxiv

Article Title: Resolving Phytophthora α2 hormone biosynthesis reveals species-specific mechanisms for mating type regulation

doi: 10.64898/2026.04.23.720443

Figure Lengend Snippet:

Article Snippet: To facilitate identification of phytol-derived metabolites, a 100 ml culture of the two strains was prepared containing either unlabeled or deuterium-labeled phytol (Toronto Research Chemicals Inc, Cat. No. TRC-T398919) at 3.4 mM.

Techniques: Labeling

Oxybenzone excretion stratified by CLDN1 rs893051 variant genotype. An excretion curve is plotted for each individual based on the excretion rate at the measured timepoints. (A–C) Excretion curves of individuals with differing genotypes at CLDN1 rs893051. (A) Individuals homozygous for the minor genotype. (B) Individuals with the heterozygous genotype. (C) Individuals homozygous for the major genotype.

Journal: Environmental and Molecular Mutagenesis

Article Title: Polymorphisms in CLAUDIN1 and SPINK5 Influence Skin Absorption of Pyrene, Pyrimethanil, and Oxybenzone in Human Volunteers

doi: 10.1002/em.70050

Figure Lengend Snippet: Oxybenzone excretion stratified by CLDN1 rs893051 variant genotype. An excretion curve is plotted for each individual based on the excretion rate at the measured timepoints. (A–C) Excretion curves of individuals with differing genotypes at CLDN1 rs893051. (A) Individuals homozygous for the minor genotype. (B) Individuals with the heterozygous genotype. (C) Individuals homozygous for the major genotype.

Article Snippet: The exposure experiment (Rietz Liljedahl et al. ) was conducted with pyrene (MilliporeSigma, Burlington, Massachusetts, USA), pyrimethanil (MilliporeSigma), and oxybenzone (Toronto Research Chemicals, Toronto, Canada) (Table ).

Techniques: Variant Assay

Oxybenzone excretion stratified by SPINK5 rs2303067 variant genotype. An excretion curve is plotted for each individual based on the excretion rate at the measured timepoints. (A–C) Excretion curves of individuals with differing genotypes at SPINK5 rs2303067. (A) Individuals homozygous for the minor genotype. (B) Individuals with the heterozygous genotype. (C) Individuals homozygous for the major genotype.

Journal: Environmental and Molecular Mutagenesis

Article Title: Polymorphisms in CLAUDIN1 and SPINK5 Influence Skin Absorption of Pyrene, Pyrimethanil, and Oxybenzone in Human Volunteers

doi: 10.1002/em.70050

Figure Lengend Snippet: Oxybenzone excretion stratified by SPINK5 rs2303067 variant genotype. An excretion curve is plotted for each individual based on the excretion rate at the measured timepoints. (A–C) Excretion curves of individuals with differing genotypes at SPINK5 rs2303067. (A) Individuals homozygous for the minor genotype. (B) Individuals with the heterozygous genotype. (C) Individuals homozygous for the major genotype.

Article Snippet: The exposure experiment (Rietz Liljedahl et al. ) was conducted with pyrene (MilliporeSigma, Burlington, Massachusetts, USA), pyrimethanil (MilliporeSigma), and oxybenzone (Toronto Research Chemicals, Toronto, Canada) (Table ).

Techniques: Variant Assay